Multiple myeloma: so much progress, but so many unsolved questions
نویسندگان
چکیده
منابع مشابه
Multiple myeloma: so much progress, but so many unsolved questions.
form the results of the first randomized study comparing conventional chemotherapy plus novel agents to tandem high-dose melphalan and ASCT in 402 newly diagnosed MM patients. At the time of the report, with a short follow up, there was no significant difference in OS between the two groups, but PFS was significantly improved in the early HDT arm. Two other ongoing trials, one conducted by the ...
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Fifteen years have elapsed since the first human infections with H5N1 highly pathogenic avian influenza (HPAI) virus were detected in Hong Kong SAR, China [1, 2]. Many of these human infections were fatal and represented the first documented outbreak of severe disease due to HPAI viruses. The hallmark of these H5N1 viruses is their hemagglutinin genes inherited from A/goose/Guangdong/1996, a vi...
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*This chapter presents and develops what is essentially a numerical method, making use of enumeration data, that distinguishes between models that are solvable, such as staircase polygons, and unsolvable, in a particular sense, such as self-avoiding polygons. The measure of solvability is whether the generating function is differentiably finite or not. Numerical methods are developed that allow...
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The free radical theory of aging is almost 60 years old. As mitochondria are the principle source of intracellular reactive oxygen species (ROS), this hypothesis suggested a central role for the mitochondrion in normal mammalian aging. In recent years, however, much work has questioned the importance of mitochondrial ROS in driving aging. Conversely new evidence points to other facets of mitoch...
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ژورنال
عنوان ژورنال: Haematologica
سال: 2013
ISSN: 0390-6078,1592-8721
DOI: 10.3324/haematol.2013.083592